Echinococcosis, or Hydatid disease/ Hydatidosis, is an infection caused by tapeworms of the genus Echinococcus, a tiny tapeworm just a few millimetres long. At least nine species within Echinococcus have been identified or designed, which infect a wide range of domestic and wild animals. Echinococcosis is a zoonosis, a disease of animals that affects humans.

Public health risk

Echinococcosis is a serious zoonosis, with rates of human cystic echinococcosis infection ranging from less than 1 per 100,000 to more than 200 per 100,000 in certain rural populations where there is close contact with domestic dogs. Incidence of human alveolar echinococcosis is usually < 0.5 per 100,000 but may be >100 per 100,000 in certain communities (e.g. Tibetan herdsmen).

Laboratory workers, animal handlers, veterinarians, dog owners are all at higher risk of infection. Since the eggs are shed in the environment, they can contaminate fruits, vegetables or water, or can stick to the fur of an animal and be transferred on hands to the mouth.

In humans the cysts of E. granulosus usually develop in organs such as the liver or lungs, so the signs of disease are due to liver or lung deficiency. Rarely, cysts form in bones causing spontaneous fractures, or in the brain causing neurological signs. Cysts or lesions of E. multilocularis occur primarily in the liver and grow slowly but with eventual serious liver pathology and high risk of mortality if untreated. As well, the cysts occasionally rupture and cause severe allergic reactions in humans.

Treatment includes surgery to remove or drain cysts or liver resection and use of long term chemotherapy with parasiticides (e.g. albendazole, mebendazole) to kill larvae or prevent them from growing back after surgery.

Since the route of infection is hand to mouth, frequent hand washing constitutes an important preventative measure.

Geographical distribution & latest situation in our region

In the Asia and the Pacific region, E. granulosus is important in Mongolia while both E. granulosus and E. multilocularis are important in China [1, 3, 6, 8, 9, 12, 13, 14, 16]. As in much of the rest of the world, the G1 genotype of the parasite is responsible for most cases of cystic echinococcosis in Mongolia and China. E. multilocularis cases in humans and wildlife were also recorded in Japan [10, 11]. While not as prevalent as in East Asia, E. granulosus has been reported in several countries in South Asia [15]. E. granulosus has been eradicated from New Zealand but remains endemic in Australia, especially down the Eastern seaboard [15].

Although less important, E. canadensis has been reported recently, within which all genotypes including G6, G7, G8 and G10 have been found to exist in humans, sheep, goats, cattle, camels, etc. [2~6].There was also an isolated report of E. ortleppi in human [7]. E. shiquicus, which was first discovered in China in 2006, is often observed in wildlife in Qinghai Tibet Plateau, and transmitted mainly between pikas and Tibet foxes [8].

Further epidemiological investigations are needed to better understand the current situation of these countries.

Regional activities

Activities and materials by members


International standards on echinococcosis

Other resources and materials on echinococcosis


  1. Zhang et al., 2015. Epidemiology and control of echinococcosis in central Asia, with particular reference to the People’s Republic of China. Acta Trop, 141: 235-243
  2. Hua et al., 2018. Echinococcus canadensis G8 Tapeworm Infection in a Sheep, China, 2018. Emerg Infect Dis. 2019 Jul;25(7):1420-1422.
  3. Ohiolei et al., 2019. Genetic variation of Echinococcus spp. in yaks and sheep in the Tibet Autonomous Region of China based on mitochondrial DNA. ; Parasit Vectors, 12(1): 608.
  4. Wu, et al., 2018. Mitochondrial genome data confirm that yaks can serve as the intermediate host of Echinococcus canadensis (G10) on the Tibetan Plateau. Parasit Vectors, 11(1): 166.
  5. Yang et al., 2015. The first report of human-derived G10 genotype of Echinococcus canadensis in China and possible sources and routes of transmission. Parasitol Int, 64(5): 330-333.
  6. Zhang et al., 2014. Genetic characterization of human-derived hydatid cysts of Echinococcus granulosus sensu lato in Heilongjiang Province and the first report of G7 genotype of E. canadensis in humans in China. PLoS One, 9(10): e109059
  7. Shi et al., 2019. First description of Echinococcus ortleppi infection in China. Parasit Vectors, 12(1): 398
  8. Han et al., 2019. Genetic characterization of Echinococcus isolates from various intermediate hosts in the Qinghai-Tibetan Plateau Area, China. Parasitology, 146(10): 1305-1312
  9. Dorjsuren et al., 2020. Prevalence and risk factors associated with human cystic echinococcosis in rural areas, Mongolia. PLoS One, 15(7): e0235399.
  10. Doi et al., 2000. Occurrence of alveolar hydatid disease (multilocular echinococcosis) outside of Hokkaido and a proposal for its prevention. Nihon Koshu Eisei Zasshi, 47(2): 111-126.
  11. Fukumoto et al., 2017. Natural larval Echinococcus multilocularis infection in a Norway rat, Rattus norvegicus, captured indoors in Hokkaido, Japan. 79(11):1857-1860.
  12. Ito et al., Histopathological, serological, and molecular confirmation of indigenous alveolar echinococcosis cases in Mongolia. Am J Trop Med Hyg, 82(2): 266-269.
  13. Ito et al., 2013. Echinococcus species from red foxes, corsac foxes, and wolves in Mongolia. Parasitology, 140(13): 1648-1654
  14. Bold et al., 2019. Evidence for camels (Camelus bactrianus) as the main intermediate host of Echinococcus granulosus sensu lato G6/G7 in Mongolia. Parasitol Res, 118(9): 2583-2590
  15. Deplazes et al., 2017, Global Distribution of Alveolar and Cystic Echinococcosis. Adv Parasitol, 95: 315-493
  16. Ito et al., 2015, The present situation of echinococcoses in Mongolia. J Helminthol, 89(c)):680-8